Hospital for Special Surgery awarded a 2-year research grant from Arthritis Foundation to support a Center of Excellence in Osteoarthritis
Patients undergoing anterior cruciate ligament (ACL) reconstruction surgery are at higher risk of developing post-traumatic osteoarthritis (PTOA), and evidence from large multicenter studies testing the efficacy of non-surgical preventive therapies is lacking.
Scott Rodeo, MD, sports medicine surgeon, vice chair of Orthopaedic Research and co-director of the Orthopaedic Soft Tissue Research Program at HSS, and Miguel Otero, PhD, associate scientist in the Orthopedic Soft Tissue Research Program at HSS, have received a 2-year research grant for $200,000 from the Arthritis Foundation to support a Center of Excellence in Osteoarthritis. As a Clinical Trial Unit of the Arthritis Foundation Osteoarthritis Clinical Trial Network (OACTN), HSS will bring its unparalleled clinical volume, including over 1,300 ACL reconstructions annually, and world-class expertise in orthopedic surgery, clinical research, molecular biology, biostatistics, and imaging, to support and strengthen the OACTN goal to test innovative interventions in multicenter randomized clinical trials (RCTs). The RCTs will integrate the use of non-surgical preventive therapies in patients at high-risk of developing PTOA, with state-of-the-art analyses of quantitative MRI, patient-reported-outcomes and biospecimens. This unique and paradigm-shifting approach has the potential to identify novel treatment approaches that could revolutionize current clinical protocols and beneficially impact patient care, both increasing quality of life and reducing financial burden.