Mortality Rates After Coronary Revascularization Procedures Among Systemic Lupus Erythematosus Compared to Diabetes Mellitus and General Population Medicaid Patients
Despite similar myocardial infarction risks in individuals with systemic lupus erythematosus (SLE) and those with diabetes mellitus (DM), SLE patients enrolled in Medicaid have substantially higher rates of coronary revascularization procedures (including coronary artery bypass grafting or percutaneous coronary intervention) compared to age- and sex-matched DM patients. Researchers evaluated 30-day mortality rates following coronary revascularization procedures among 608 SLE compared to 1,185 DM and 628 general population patients enrolled in Medicaid. Although based on a small number of post-procedural deaths in each of the groups, investigators found that SLE patients had 1.7 times higher 30-day mortality rates after coronary revascularization compared to DM and general population patients, despite being on average much younger when they had the procedure. After adjusting for demographics and comorbid index lupus patients had double the odds of death within 30 days after a coronary revascularization compared to patients with DM. They also found a similar, but non-significant result for SLE patients compared to the general population, although this was limited by very few deaths in the general population group. The researchers wrote that “future studies accounting for healthcare utilization, the complexity and indications of the procedures performed, SLE and cardiac disease severity, and investigating causes of post-procedure deaths are required.”
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