17:19 PM

PROMIS10 measurement responsive to patient-reported changes in lupus


Healio Rheumatology reports on study findings published in Arthritis Care & Research, which showed The Patient-Report Outcomes Measurement Information Systems global health short form is responsive to patient-reported- but not physician-reported changes in lupus.

PROMIS10, a 10-item global PRO instrument, was developed as part of the National Institutes for Health Roadmap initiative to create a resource for accurate and efficient measurement of patient-reported symptoms, functioning and health-related quality of life across medical conditions. To analyze the responsiveness of PROMIS10 among patients with Systemic Lupus Erythematosus (SLE), researchers conducted a prospective, longitudinal study of adults who received outpatient care at the HSS Lupus Center of Excellence. A total of 223 patients with SLE completed baseline PROMIS10 assessments at the first of two visits, conducted at least 1 month apart. Of those initial participants, 186 completed the second set of questionnaires. Participants also completed the Short Form-36 (SF-36) assessment.

PROMIS10 demonstrated mild-to-moderate responsiveness to patient-reported improvement, and worsening, of health status for both physical and mental health domains. However, PROMIS10 performed poorly in responding to changes in physician reported measures of disease activity.

Read the full article at Healio.com.