Healio Rheumatology reports on study findings published in Arthritis Care & Research, which showed The Patient-Report Outcomes Measurement Information Systems global health short form is responsive to patient-reported- but not physician-reported changes in lupus.

PROMIS10, a 10-item global PRO instrument, was developed as part of the National Institutes for Health Roadmap initiative to create a resource for accurate and efficient measurement of patient-reported symptoms, functioning and health-related quality of life across medical conditions. To analyze the responsiveness of PROMIS10 among patients with Systemic Lupus Erythematosus (SLE), researchers conducted a prospective, longitudinal study of adults who received outpatient care at the HSS Lupus Center of Excellence. A total of 223 patients with SLE completed baseline PROMIS10 assessments at the first of two visits, conducted at least 1 month apart. Of those initial participants, 186 completed the second set of questionnaires. Participants also completed the Short Form-36 (SF-36) assessment.

PROMIS10 demonstrated mild-to-moderate responsiveness to patient-reported improvement, and worsening, of health status for both physical and mental health domains. However, PROMIS10 performed poorly in responding to changes in physician reported measures of disease activity.

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