Millions of Americans are taking or considering GLP-1 medications for weight loss and diabetes management, or thinking of starting them. But HSS experts say there is an important consideration patients should understand before starting treatment: rapid weight loss can lead to a loss of muscle mass and bone density. 

In an article published to Fortune, Jessica Starr, MD, endocrinologist at HSS, and Emily Stein, MD, MS, Co-Director of the Skeletal Health Orthopaedic Research Program at HSS, recommend that patients taking GLP-1 medications work closely with their physicians and incorporate exercise and strength training into their treatment plans to preserve long-term musculoskeletal health.

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