12:52 PM

Studies could shed light on treatment response in RA

Healio Rheumatology reports on two new HSS studies by co-senior author Laura Donlin, PhD, and collaborating colleagues, which demonstrated newly discovered subsets of cells found in joint tissue among patients with rheumatoid arthritis (RA), and how they interact could potentially explain why only certain individuals respond to current treatments.

In the first paper published in Nature Immunology, Dr. Donlin collaborated within the Accelerating Medicines Partnership (AMP) in Rheumatoid Arthritis and Lupus Network (AMP RA/SLE consortium) to create a comprehensive “map” of the cells found in RA joint tissue using advanced technologies. As a result, 18 unique cell populations in synovial tissue provided by patients with RA were identified. In the second paper, published in the journal Science Translational Medicine, Dr. Donlin and HSS colleagues conducted additional research using the results from the AMP consortium to focus on the activity of a particular disease-associated cell type.

Read the full article at Healio.com.

Additional coverage: NIH Research Matters