Becker's Spine Review reported on six orthopedic studies to know featuring a recent HSS research study that found orthopedic patients responded well to a new nonopioid pain reliever. 

Suzetrigine is the first nonopioid pain reliever released in more than two decades. It was approved by the FDA in January 2025 and became available at HSS in April 2025.

The study evaluated 103 patients who took suzetrigine after undergoing a surgical procedure, mostly joint arthroplasty or spine surgery, at HSS. Eight patients experienced an adverse reaction, but the remaining 95 generally tolerated the medication well. 

Read the full article at beckersspine.com.